Shikonin-into entsha yendalo yokulwa nebhaktiriya eyenza inguquko ye-antibiotic
Kungekudala, izazinzulu ziye zafumanisa into entsha ye-antibacterial yendalo, i-shikonin, kwi-treasure trove yezityalo. Oku kufunyenweyo kuye kwavusa ingqalelo kunye nochulumanco kwihlabathi liphela. I-Shikonin inomsebenzi obanzi we-antibacterial kwaye ilindeleke ukuba ibe ngumviwa obalulekileyo ekuphuhliseni i-antibiotics entsha. IShikonin ithathwa kwisityalo ekuthiwa yicomfrey, esikhula kwiindawo zaseAsia, eYurophu nakuMntla Merika. IShikonin inombala omfusa ocacileyo kwaye isetyenziswa kakhulu kwidayi nakumayeza esintu. Nangona kunjalo, uphando olutshanje lubonisa ukuba i-shikonin ayikho nje into enhle, kodwa kunye ne-antibacterial agent enokubakho.
Kwiimvavanyo, izazinzulu zafumanisa ukuba i-shikonin inempembelelo enamandla yokuthintela kwiintlobo zebhaktheriya kunye nefungi. Ayiphelelanga apho, inokuba nefuthe le-bactericidal kwezinye iibhaktiriya ezinganyangekiyo ngamachiza, nto leyo ibaluleke kakhulu kwingxaki enzima yangoku yokunganyangeki ngamayeza okubulala iintsholongwane. Abaphandi baye bafumanisa ukuba i-shikonin inokusebenzisa i-antibacterial effect ngokutshabalalisa i-membrane yeseli yebhakteria kunye nokuvimbela ukukhula kwayo. Lo matshini uhlukile kumachiza e-antibacterial ekhoyo, enika isikhokelo esitsha sophuhliso lwe-antibiotics. Ukuze kuqinisekiswe ngakumbi ukusebenza kunye nokhuseleko lwe-shikonin, abaphandi baqhube uchungechunge lwe-vivo kunye ne-in vitro experiments.
Into evuyisayo kukuba i-shikonin ibonise umsebenzi omhle webhayoloji ngaphandle kokubangela iziphumo ezibi. Oku kwenza i-shikonin ibe yi-arhente echasene ne-antibacterial kwaye ifake ubutsha obutsha kuphando kunye nophuhliso lwe-antibiotics. Nangona ukufunyanwa kwe<em>shikonin kuzise ithemba, izazinzulu zikwakhumbuza abantu ukuba ukuphuhliswa nokusetyenziswa kwe<em>antibacterial agents kufuneka kulumke. Ukusetyenziswa kakubi nokusetyenziswa kakubi kwee-antimicrobial kuye kwakhokelela kwintlekele yehlabathi lonke yokunganyangeki kweyeza, ngoko kufuneka kusetyenziswe amayeza amatsha kwaye kulawulwe ngokufanelekileyo.
Ukongeza, izazinzulu zaphinda zacela abatyali-mali kunye norhulumente ukuba banyuse inkxaso-mali kunye nenkxaso yophando lwe-antimicrobial kunye nophuhliso ukukhuthaza ukuphuhliswa kwamachiza amatsha. Okwangoku, uphando nge-shikonin lutsale umdla kwihlabathi liphela. Inani leenkampani zamachiza kunye namaziko ophando aqhubela phambili uphando kunye nophuhliso lwee-antibacterial agents ezinxulumene ne-shikonin.
Abaphandi bathi baya kuqhubeka befunda ubume bemolekyuli kunye nenkqubo yesenzo se-shikonin ukuze baphonononge ngcono amandla ayo. Ngenkqubela phambili eqhubekayo kwintsimi yamachiza e-antibacterial, ukufunyanwa kwe-shikonin kuye kwafaka impembelelo entsha kwi-revolution ye-antibiotic. Inika ithemba kwaye ibeka isiseko sesizukulwana esitsha samayeza okulwa neentsholongwane. Sinokubona kwangaphambili ukuba uphando lwe-shikonin luya kukhuthaza ukutsha kwintsimi yeyeza kunye nokuzisa ukhetho oluninzi kunye nethemba kwimpilo yabantu.
Ixesha lokuposa: Jul-27-2023
