Fisetin, ibala elityheli lendalo eliphuma kwisityalo segentian, liye lamkelwa ngokubanzi luluntu lwenzululwazi ngesakhono saso kwicandelo lokufunyanwa kweziyobisi. Uphononongo lwakutsha nje lubonise ukuba i-fisetin inemisebenzi ebalulekileyo kwi-antibacterial, anti-inflammatory and anti-tumor aspects, evuse umdla omkhulu kwizazinzulu. I-Fisetin inembali ende kwimbali yamayeza aseTshayina kwaye isetyenziswa ngokubanzi njengesithako kumayeza esintu.
Nangona kunjalo, kwakutsha nje ukuba izazinzulu zaqala ukuphanda kubume bemichiza kunye neziphumo zekhemesti zefisetin. Abaphandi bakhupha i-substance kwisityalo se-gentian kwaye bafumana iisampulu ezininzi ngokusebenzisa i-chemical synthesis, okwenza uphando olongezelelweyo lunokwenzeka. Iziphumo zovavanyo zakwangoko zibonisa ukuba i-fisetin ineempembelelo ze-antibacterial kwiibhaktheriya ezahlukeneyo. Iimvavanyo ezichasene neentlobo ezinganyangekiyo ngamachiza zibonise ukuba i-fisetin inokuthintela ngokubonakalayo ukukhula kwayo, kwaye inamandla abalulekileyo osulelo oluqhelekileyo lweklinikhi lwebhaktiriya. Ukufunyaniswa kuzisa ithemba elitsha kwingxaki yokunganyangeki ngamayeza okubulala iintsholongwane, ngakumbi kunyango lwezifo ezifunyenwe esibhedlele. Ukongezelela, i-fisetin ifunyenwe ibe nemiphumo emihle yokuchasana nokuvuvukala. Ukuvuvukala yinto eqhelekileyo yezifo ezininzi, kuquka i-arthritis, isifo sesibindi esivuthayo kunye nesifo senhliziyo.
Abaphandi abafunyenwe ngovavanyo lwezilwanyana ukuba i-fisetin inokunciphisa kakhulu impendulo yokuvuvukala kunye nokunciphisa izinga labamakishi abavuthayo. Oku kunika indlela entsha yokusebenzisa i-fisetin kunyango lwezifo ezivuthayo. Eyona nto ikhuthazayo, ezinye izifundo zokuqala zibonisa ukuba i-fisetin inokuba namandla okulwa ne-antitumor. Iziphumo zovavanyo zibonisa ukuba i-fisetin inokuthintela ukukhula kunye nokusasazeka kweeseli ze-tumor, ngelixa zinempembelelo encinci kwiiseli eziqhelekileyo. Oku kubonelela ngombono omtsha wokuphuhliswa kwamachiza asebenzayo kunye nokhuseleko lwe-antitumor.
Nangona uphando lwefisetin lusekwinqanaba lokuqala, ukusetyenziswa kwechiza elinokubakho kufanelekile ukujongwa kulo. Iingcali zenzululwazi zihlola kwiindlela ze-fisetin ukuze ziqonde ngcono indima yayo kwiindawo zebhaktheriya, ukuvuvukala kunye namathumba. Kwixesha elizayo, izazinzulu ziya kuqhubeka nokusebenza nzima ukufumana i-fisetin derivatives efanelekileyo okanye ukulungiswa kwesakhiwo ukuphucula umsebenzi wayo kunye nokuzinza. Kuphando kunye nophuhliso lwefisetin, izixhobo ezaneleyo kunye nenkxaso ziyafuneka. Urhulumente, amaziko ophando lwenzululwazi kunye neenkampani zoxubo mayeza kufuneka zomeleze intsebenziswano kwaye ngokudibeneyo batyale imali eninzi kunye nabasebenzi ukukhuthaza uphando olongezelelweyo kwifisetin. Ngexesha elifanayo, imimiselo efanelekileyo kunye nemigaqo-nkqubo nayo kufuneka ihambisane namaxesha okubonelela ngenkxaso kunye nokukhuselwa kophando lokuthotyelwa kwe-fisetin kunye ne-derivatives yayo.
Njengeyeza lendalo elinokubakho, i-fisetin inika ithemba kubantu ukuba bafumane unyango olutsha. Izazinzulu zinomdla ngophando lwefisetin. Kukholelwa ukuba kwikamva elingekude, i-fisetin iya kuba nendima ebalulekileyo kwicandelo lamayeza kwaye izise iindaba ezilungileyo kwimpilo yabantu. Sijonge phambili ekufumaneni uphando ngakumbi kunye nenkqubela phambili yokukhuthaza ukusetyenziswa kunye nophuhliso lwefisetin. Qaphela Eli nqaku linqaku elingeyonyani kuphela. Njengesithako sendalo, i-fisetin idinga uphando lwezenzululwazi ngakumbi kunye nolingo lweklinikhi ukuqinisekisa isiphumo sayo sonyango esinokubakho.
Ixesha lokuposa: Jul-06-2023
