Aminobutyric acid(I-Gamma-Aminobutyric Acid, efinyeziweyo njenge-GABA) ibaluleke kakhulu i-amino acid ekhoyo kwingqondo yomntu kunye nezinye izinto eziphilayo. Idlala indima ye-inhibitory transmitter kwinkqubo ye-nervous, enokukunceda ukulawula umsebenzi wenkqubo ye-nervous central kunye nokugcina ukulinganisela kweempawu ze-nerve. Uphando kwiminyaka yakutshanje lubonise ukuba i-GABA ineenzuzo ezahlukeneyo kwimpilo yabantu, ukusuka ekuphuculeni umgangatho wokulala ukuya ekunciphiseni ixhala, uxinzelelo, njl., Ukubonisa amandla amangalisayo. Uphononongo lwakutsha nje lubonise ukuba i-GABA inefuthe elibonakalayo ekuphuculeni umgangatho wokulala. Ukulala kuthathwa njengenkqubo yomzimba yokulungisa kunye nokuvuselela, kwaye umgangatho ophantsi wokulala unokuba nefuthe elibi kwimpilo yabantu. I-GABA inokulawula i-nerve conduction kunye ne-inhibition ngokuchaphazela i-GABA receptors kwingqondo, kwaye ikhuthaze ukuphumla komzimba kunye nokulala. Uphononongo lufumene ukuba ukusebenzisa izongezelelo ze-GABA kunokunciphisa kakhulu ixesha lokulala, ukuphucula umgangatho kunye nobude bokulala, kunye nokunciphisa inani lokuvuka ebusuku, ngaloo ndlela kunceda abantu ukuba bafumane ukuphumla okungcono kunye nokubuyisela. Ukongeza kwiinzuzo zayo ekuphuculeni ubuthongo, i-GABA nayo ibonakaliswe ekuncedeni ukuxhalaba kunye noxinzelelo. Ubomi boxinzelelo oluphezulu kunye nemeko yomsebenzi okhawulezayo wentlalo yanamhlanje yenza abantu abaninzi bajongane namanqanaba ahlukeneyo okuxhalaba kunye noxinzelelo. I-GABA inokunciphisa ukukhululwa kwe-glutamate ye-neurotransmitter ngokusebenzisana ne-GABA receptors, ngaloo ndlela inciphisa ukukhululeka kwenkqubo ye-nervous kunye nokunciphisa ixhala kunye noxinzelelo. Uphononongo lubonise ukuba ukuxhaswa kwexesha elide le-GABA kunokunciphisa kakhulu iimvakalelo zokuxhalaba kunye noxinzelelo, kunye nokuphucula impilo yengqondo kunye nokuphila kakuhle. Ukongeza, i-GABA inokunceda ukuxhasa umsebenzi wokuqonda kunye nempilo yengqondo. Ingqondo lelinye lawona malungu abalulekileyo emzimbeni womntu kwaye ibalulekile ekusebenzeni ngokufanelekileyo kokuqonda kunye nokucinga. Izifundo zifumene ukuba i-GABA inokukhuthaza umsebenzi we-GABA receptors, ichaphazela ukuhanjiswa kwesignali kunye nomsebenzi we-neuron kwingqondo, ngaloo ndlela iphucula ingqalelo, ikhono lokufunda kunye nememori. Iziphumo zivula amathuba amatsha okujongana nokuguga kunye nokuthintela izifo ezifana ne-Alzheimer's. Njengoko uphando kwi-GABA luqhubeka lunzulu, iimveliso ezininzi zezempilo kunye nokutya okunempilo ziqala ukongeza i-GABA njengesithako esibalulekileyo. Ukususela kwizongezelelo zomlomo ukuya kwiziselo, ukutya, njl., Uluhlu lwesicelo se-GABA lukhula rhoqo. Nangona kunjalo, abathengi kufuneka banikele ingqalelo kumgangatho kunye nomthombo weemveliso xa kuthengwa iimveliso ze-GABA, kwaye bakhethe iimpawu ezithembekileyo kunye neemveliso. Ukusetyenziswa okubanzi kwe-GABA kuhambelana ngokusondeleyo nemiphumo emihle yempilo. Ayinako nje ukubonelela umgangatho wobuthongo ophuculweyo, ukuthomalalisa ixhala kunye noxinzelelo, kodwa inokuphucula ukusebenza kwengqondo kunye nokuphucula impilo yengqondo. Kwixesha elizayo, kunye nophando olunzulu kwi-GABA kunye nokuqwalaselwa kwabantu okuqhubekayo kwimpilo, kukholelwa ukuba i-GABA iya kudlala indima ebalulekileyo yezempilo kwaye incede abantu bafezekise umgangatho wobomi obungcono.
Ixesha lokuposa: Jul-24-2023
